Meet SynHealth coordinator Genos
The project is led by coordinator Genos, based in Zagreb, Croatia. Meet the organization and its team and find out more about their accomplishments in the healthcare ecosystem and more specifically of high-throughput glycomids in personalized medicine.
Genos laboratory
Genos is an SME and the leading research institution in Croatia.
In 2007, it received official recognition as a research institution from the Croatian Ministry of Science, resulting in its inclusion in the national Registry of Research Organisations. Then, in 2017, the Croatian Agency for Science and Higher Education initiated a mandatory accreditation of Genos as a research organization confirming it as a research organization within the domains of “Natural Sciences” and “Biomedicine and Health.” Subsequently, in 2020, the Ministry of Science officially welcomed Genos as a research organization.
Genos has participated in numerous European Union research initiatives, including the FP7 projects GlycoBioM (grant #259869), HighGlycan (grant #278535), IBD-Biom (grant #305479)…
Under Horizon 2020, Genos researchers further participated in numerous projects, amongst which GlycoCan (grant #676421), GlySign (grant #722095), SYSCID (grant #733100) etc.
Currently, The organization collaborates as a partner in the IMI2 project 3TR (grant #831434) and the ERC Synergy project GlycanSwitch (grant #101071386).
Genos researchers publish over 30 research papers per year in prestigious journals, and their studies are cited over 2500 times per year (according to Google Scholar). Currently, it employs 50 researchers.
Genos’ research focuses on the application of high-throughput glycomics in personalized medicine. The Genos research team pioneered high-throughput glycomics fifteen years ago, marked by their initial population study of the total plasma glycome involving 1000 individuals from Croatia’s Vis island. In 2011, they performed the first comprehensive population study of an individual glycoprotein (IgG). Over the years, they have analyzed glycomes of more than 200,000 individuals participating in numerous clinical and epidemiological studies. A recent comprehensive review published in Chemical Reviews demonstrated that Genos has examined more than 80% of all glycomes published as part of large clinical and epidemiological studies in the last 15 years.
The laboratory in Zagreb houses an array of advanced equipment, including seven Waters Acquity H class UPLC instruments with fluorescent detectors, an Exploris 240 Orbitrap with NCS-3500 UHPLC, two Waters nano-UPLCs with Bruker Compact qTOF detectors, two 4-capillary Avant 3130 DNA sequencers, two 8-capillary Avant 3500 DNA sequencers used for glycan analysis, and a Tecan EVO 200 robot with an external positive pressure module. This comprehensive suite of equipment is supplemented by various smaller supportive devices.
In 2013, The Scientist magazine ranked Genos as “the place to work for researchers in industry” worldwide. A decade later, this recognition remains valid, given that most researchers affiliated with Genos in 2013 still work there. Employee loyalty has significantly contributed to the accumulation of specialized expertise within Genos.
Meet the team!
Gordan Lauc
Gordan Lauc is a Professor of Biochemistry and Molecular Biology at the University of Zagreb, Director of the National Centre of Scientific Excellence in Personalized Healthcare, Honorary professor at the Kings College London and member of the Johns Hopkins Society of Scholars.
In 2017 he initiated the launch of the Human Glycome project and is one of its two co-directors. His research team is pioneering high throughput glycomic analysis and the application of glycan biomarkers in the field of precision medicine.
Professor Lauc co-authored over 300 research articles that are cited over 15,000 times in Google Scholar. In 2007 he founded Genos, a biotech company that is currently a global leader in high-throughput glycomics. Research in Genos led to the development of the GlycanAge test of biological age.
Ivana Gulišija Radić
Ivana joined Genos in 2023 as a Research Manager with a unique blend of skills derived from both the business world and science. Her mission is to harmonize business practices with scientific endeavors, fostering innovation, and contributing to the expansion of knowledge.
She graduated with a degree in economics from the University of Split in 2015, earning the title of Professional Master in Business. With a keen interest in human health and science, she furthered her education in 2021 by successfully obtaining a Master of Science degree in Microbiology from the University of New Mexico.
Azra Frkatović-Hodžić
Azra is a researcher with a background in genetics, having obtained her Master’s degree in 2017 from Burch University in Sarajevo, Bosnia and Herzegovina. She then pursued a PhD degree in biology at the University of Zagreb while working as an early stage researcher in IMforFUTURE network at Genos.
During her PhD studies, Azra focused on utilizing computational approaches to explore the genetic basis of IgG glycosylation. She successfully completed her PhD in 2022 and continued her work at Genos.
- Terms: #biomarkers, #business, #healthcare, #innovation, #tech
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